Signos launches first FDA-cleared over-the-counter glucose monitoring system for weight management

OTC glucose monitor launches: ©Andrey Popov - stock.adobe.com

Signos announced the launch of what it calls the first-ever FDA-cleared, over-the-counter glucose monitoring system designed specifically for weight management.

The Signos Glucose Monitoring System combines Dexcom’s Stelo glucose biosensor with an artificial intelligence-powered platform that provides real-time insights into how food, exercise, stress, and sleep affect the body. Unlike traditional glucose monitors that are primarily used for diabetes care, the system is positioned as a tool for individuals looking to better manage their weight and overall metabolic health.

“This is more than a product launch—it’s a mission,” said Sharam Fouladgar-Mercer, CEO and founder of Signos, in a statement. “Everyone deserves access to insights that help them live healthier, longer, more vibrant lives. Signos isn’t just about data; it’s about giving people ownership over their health and weight journeys in a way never before seen.”

The company said the device translates glucose fluctuations into personalized recommendations, giving users a clearer picture of how their lifestyle choices affect metabolism. By offering the system without a prescription, Signos said it is lowering barriers to care at a time when nearly three-quarters of U.S. adults are classified as overweight or obese, and global diabetes cases are expected to reach 1.3 billion by 2050.

Actress Raven-Symoné, an advisor to the company, said in a statement that using the system has helped her stay mindful of her health while enjoying life.

The system is now available to consumers through their smartphones, giving them what the company calls “real-time metabolic health, made truly accessible.”

Advances in metabolic health technology

The launch of over-the-counter glucose monitoring tools highlights a broader shift in metabolic health technology, where innovation is making once-specialized devices more accessible to the public. Traditionally, continuous glucose monitors were developed and prescribed for patients with diabetes, offering clinicians precise, real-time data to manage blood sugar levels. Now, those same technologies are being adapted for general health and weight management, extending their reach to a much larger population.

Recent advances have been driven by the convergence of wearable biosensors, artificial intelligence, and personalized health platforms. Biosensors can now measure glucose levels continuously and with greater accuracy, while AI-driven algorithms translate this complex data into easy-to-understand recommendations. These tools not only track blood sugar fluctuations but also connect them to lifestyle factors such as diet, exercise, sleep, and stress, creating a more holistic view of health.

Another notable trend is the shift toward prevention and proactive care. With obesity and metabolic disorders on the rise globally, companies and researchers are focusing on tools that empower individuals to take charge of their health earlier, before chronic conditions develop. By giving users real-time feedback, these systems encourage behavior changes that can support weight management, improve sleep, and reduce long-term health risks.

The democratization of metabolic health monitoring also reflects broader movements in digital health. As technology becomes more affordable and available without prescriptions, it is moving from the clinic into the everyday lives of consumers. This transition raises new questions about regulation, data privacy, and the balance between consumer wellness tools and medical devices. Still, experts say the momentum suggests that real-time metabolic insights could become a standard feature of personal health management in the coming years.