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Got the flu? Have some chocolate; centenarians age differently; August APA journals are out now – Morning Medical Update

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Key Takeaways

  • A drug combo with theobromine outperforms Tamiflu against flu, including drug-resistant strains, by blocking a viral ion channel, potentially leading to more durable antivirals.
  • Centenarians develop fewer diseases at a slower pace, with disease burden leveling off after age 90, and fewer cardiovascular and neuropsychiatric conditions.
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Morning Medical Update © meeboonstudio - stock.adobe.com

Chocolate-based combo outperforms Tamiflu

A surprising new drug combo — featuring theobromine, a compound found in chocolate — has outperformed Tamiflu in fighting the flu, including drug-resistant bird and swine strains. Researchers at Hebrew University say the combo blocks a key viral ion channel, cutting off replication in both cell and animal models. Published in PNAS, the study suggests this novel approach could lead to more durable antivirals and even help prepare for future pandemics. Human trials are expected next.

Centenarians age differently

New research from Karolinska Institutet shows that centenarians not only live longer but develop fewer diseases, and at a slower pace, than their peers. Published in eClinicalMedicine, the study found that disease burden levels off after age 90 and that cardiovascular and neuropsychiatric conditions are less common in those who live to 100.

August APA journals out now: genetics, telehealth risks and advocacy in focus

The latest issues of APA’s American Journal of Psychiatry, Psychiatric Services and Focus are out now, with studies on ADHD genetics, telehealth stimulant prescribing, youth recidivism and gaps in perinatal mental health. A special issue of Focus — guest-edited by The Kennedy Forum — highlights how psychiatrists can drive policy change.

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