The incidence of severe chronic obstruction pulmonary disorder (COPD) exacerbations has increased in recent years in France, according to the results of a study published in Respiratory Research. Additionally, the number of patients admitted to the intensive care unit (ICU) for these exacerbations has also increased.
“COPD admissions are increasing in incidence and direct expenses and, despite modifications of management, mortality is also increasing,” study researcher Arnaud Bourdin, MD, of the University of Montpellier, France, told Medical Economics.
Bourdin and colleagues conducted this observational study to look at trends in mortality, costs and in-hospital management and outcomes for patients with severe COPD exacerbations admitted to the hospital in France. According to Bourdin, studying the incidence of COPD exacerbations is important because they are a marker of the burden of the disease over time.
The researchers obtained data for the study from the French admissions registry, looking at six consecutive years of severe COPD exacerbations leading to hospitalizations. Data were collected from 2007 to 2012. The researchers defined hospitalization as a stay of at least one night in a hospital, and included only those patients with the International Classification of Disease-10 code for COPD as a primary diagnosis. Patients were split into four groups; those with hospitalization in a general ward without acute respiratory failure, general ward with acute respiratory failure, ICU without invasive mechanical ventilation and ICU with mechanical ventilation.